gwlilabmit / gwlilabmit/rendseq

Current Z-score outlier removal method is resulting in increased number of false positives.

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Description

The current method for outlier removal (eg removing the top x% in an ordered list) seems to be resulting in a large number of false positives. Recommendation to replace this method with a numpy optimized version of the original mean/sd based approach and/or to to make the number of reads excluded a tunable parameter. Thanks to @jxmavs for raising this issue and for suggestions!

Examples of false positives (at z score 14) (false z score in center of frame). Thanks to James for collecting examples:

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