griffithlab / griffithlab/pVACtools
Use MHCgnomes to help resolve HLA alleles
Nobody has claimed this yet.
- Dominant language
- Python
- Stars
- 188
- Forks
- 81
- Avg merge
- 9d 17h
- Merged PRs (30d)
- 6
Description
These folks have built what looks to be a nice tool for mapping HLA nomenclature (which is all over the place) into standardized formats: https://github.com/pirl-unc/mhcgnomes
Could be user-friendly if pvactools was able to resolve weird hla notation into the proper form using this tool. (or at least, maybe we could provide a link in the FAQ for folks having issues?)
Contributor guide
No contributing guide indexed for this repository
First steps
- Read the whole issue, then the project's contributing guide.
- Comment on the issue to say you are picking it up — it saves two people doing the same work.
- Fork the repository and make your change on a branch.
- Open a pull request that references the issue number.
Research direction
Start by reviewing pVACtools' existing HLA input and allele-resolution handling, then inspect the linked MHCgnomes project. Decide whether the work should integrate standardized resolution or only add an FAQ link; done when the chosen behavior and supported notation are clearly documented and tested.
Written by the indexing model from the issue text.
Assessment
- Tech stack
- python
- Domain
- bioinformatics
- Issue type
- Feature
- Difficulty
- 5/5
- Estimated time
- Over a week
- Activity status
- Stale
- Clarity
- Needs clarification
- Newbie friendliness
- 25/100