griffithlab / griffithlab/pVACtools
Consider use of APE-Gen algorithm
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prediction_algorithms
- Dominant language
- Python
- Stars
- 188
- Forks
- 81
- Avg merge
- 9d 17h
- Merged PRs (30d)
- 6
Description
From the ITCR meeting. APE-Gen would be quite orthogonal to the current algorithms for pMHC prediction as it is based on 3D structure modeling of the pMHC
Contributor guide
No contributing guide indexed for this repository
First steps
- Read the whole issue, then the project's contributing guide.
- Comment on the issue to say you are picking it up — it saves two people doing the same work.
- Fork the repository and make your change on a branch.
- Open a pull request that references the issue number.
Research direction
Start by reading the linked APE-Gen repository and identifying the current pMHC prediction entry points in pVACtools. Compare how APE-Gen's 3D structure modeling could fit alongside the existing algorithms; the issue does not define an implementation scope or a concrete done condition.
Written by the indexing model from the issue text.
Assessment
- Tech stack
- python
- Domain
- bioinformatics
- Issue type
- Feature
- Difficulty
- 5/5
- Estimated time
- Over a week
- Activity status
- Stale
- Clarity
- Needs clarification
- Newbie friendliness
- 20/100