griffithlab / griffithlab/pVACtools

Investigate PUFFIN algorithm

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grant prediction_algorithms
Dominant language
Python
Stars
188
Forks
81
Avg merge
9d 17h
Merged PRs (30d)
6

Description

As discussed at recent Immunotherapy Tumor Board meeting, Max Artyomov, mentioned this algorithm as promising: https://pubmed.ncbi.nlm.nih.gov/31176619/

Contributor guide

No contributing guide indexed for this repository

First steps

  1. Read the whole issue, then the project's contributing guide.
  2. Comment on the issue to say you are picking it up — it saves two people doing the same work.
  3. Fork the repository and make your change on a branch.
  4. Open a pull request that references the issue number.

Research direction

Start by reading the linked PubMed paper on the PUFFIN algorithm and comparing its requirements with pVACtools. The issue names no files, tests, or entry points, and completion criteria are not defined; clarify whether the goal is an implementation, an integration, or an evaluation before proceeding.

Written by the indexing model from the issue text.

Assessment

Tech stack
python
Domain
bioinformatics
Issue type
Feature
Difficulty
5/5
Estimated time
Over a week
Activity status
Stale
Clarity
Needs clarification
Newbie friendliness
20/100

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