griffithlab / griffithlab/pVACtools

Incorporate Patient Harmonic-mean Best Rank (PHBR) into class I report

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grant
Dominant language
Python
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188
Forks
81
Avg merge
9d 17h
Merged PRs (30d)
6

Description

The Patient Harmonic-mean Best Rank (PHBR) score is highly influenced by the best allele but also integrates information about presentation by the other alleles.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711564/

Contributor guide

No contributing guide indexed for this repository

First steps

  1. Read the whole issue, then the project's contributing guide.
  2. Comment on the issue to say you are picking it up — it saves two people doing the same work.
  3. Fork the repository and make your change on a branch.
  4. Open a pull request that references the issue number.

Research direction

No file, test, or entry point is named. Start by reading the linked PHBR paper and locating the current class I report implementation; done means the report incorporates the PHBR score with behavior covered by suitable tests.

Written by the indexing model from the issue text.

Assessment

Tech stack
python
Domain
bioinformatics
Issue type
Feature
Difficulty
5/5
Estimated time
Over a week
Activity status
Stale
Clarity
Needs clarification
Newbie friendliness
25/100

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