griffithlab / griffithlab/pVACtools

Implement a pathogen similarity score

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feature addition grant
Dominant language
Python
Stars
188
Forks
81
Avg merge
9d 17h
Merged PRs (30d)
6

Description

Test candidate peptides for similarity to known immunogenic peptides (e.g. in IEDB) and report this feature.

Contributor guide

No contributing guide indexed for this repository

First steps

  1. Read the whole issue, then the project's contributing guide.
  2. Comment on the issue to say you are picking it up — it saves two people doing the same work.
  3. Fork the repository and make your change on a branch.
  4. Open a pull request that references the issue number.

Research direction

No file, test, or entry point is named. First clarify how candidate peptides and known immunogenic peptides from IEDB should be represented and compared, including the expected score and report format. Done means the tool calculates and reports the agreed pathogen-similarity feature.

Written by the indexing model from the issue text.

Assessment

Tech stack
python
Domain
bioinformatics
Issue type
Feature
Difficulty
5/5
Estimated time
Over a week
Activity status
Stale
Clarity
Needs clarification
Newbie friendliness
25/100

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