griffithlab / griffithlab/civicpy

Support GRCH37 to 38 conversion

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Dominant language
Python
Stars
13
Forks
8
PR merge metrics
No merged PRs in 30d

Description

We've had users request that we provide GRCH38 coordinates. So either a query that could find CIViC evidence using 38 coordinates as a query, or a CIViC converter that just supplies EIDs of interest with 38 coordinates annotated as well (potentially the whole dataset).

Contributor guide

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First steps

  1. Read the whole issue, then the project's contributing guide.
  2. Comment on the issue to say you are picking it up — it saves two people doing the same work.
  3. Fork the repository and make your change on a branch.
  4. Open a pull request that references the issue number.

Research direction

The issue names no files, tests, or entry points. First clarify whether the goal is querying CIViC evidence with GRCh38 coordinates or producing a converter with GRCh38 annotations, and define the dataset scope. Done means one agreed approach supports the requested GRCh38 coordinate use case.

Written by the indexing model from the issue text.

Assessment

Tech stack
python
Domain
data, databases
Issue type
Feature
Difficulty
5/5
Estimated time
Over a week
Activity status
Stale
Clarity
Needs clarification
Newbie friendliness
25/100

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