google-deepmind / google-deepmind/alphafold

unclear technical note on AlphaFold v2.3.0

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Description

In the [Technical Note](https://github.com/deepmind/alphafold/blob/main/docs/technical_note_v2.3.0.md) it states the following:

> In cases where the stoichiometry is unknown, such as in genome-scale prediction, it is likely that single chain AlphaFold will be more accurate on average unless the chain has several thousand residues.

Does this mean that if there's a chance your single chain is part of a multimer with unknown stoichiometry then the older version of AlphaFold will be more accurate?

If you're just looking at monomers, then the new AlphaFold v.2.3.0 in multimer mode to be preferred?

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