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CE8eSpRY.fasta
报错：I0910 11:42:53.106589 139985805367104 hhsearch.py:76] Launching subprocess "hhsearch -i /tmp/tmpd42j2lo8/query.a3m -o /tmp/tmpd42j2lo8/output.hhr -maxseq 1000000 -d /mnt/pdb70/pdb70"
I0910 11:42:53.259523 139985805367104 utils.py:36] Started HHsearch query
I0910 11:42:53.617978 139985805367104 utils.py:40] Finished HHsearch query in 0.358 seconds
Traceback (most recent call last):
File "run_alphafold.py", line 338, in
app.run(main)
File "/home/alphafold/miniconda3/envs/alphafold/lib/python3.8/site-packages/absl/app.py", line 312, in run
_run_main(main, args)
File "/home/alphafold/miniconda3/envs/alphafold/lib/python3.8/site-packages/absl/app.py", line 258, in _run_main
sys.exit(main(argv))
File "run_alphafold.py", line 310, in main
predict_structure(
File "run_alphafold.py", line 170, in predict_structure
feature_dict = data_pipeline.process(
File "/home/alphafold/alphafold/alphafold/data/pipeline.py", line 166, in process
hhsearch_result = self.hhsearch_pdb70_runner.query(uniref90_msa_as_a3m)
File "/home/alphafold/alphafold/alphafold/data/tools/hhsearch.py", line 85, in query
raise RuntimeError(
RuntimeError: HHSearch failed:
stdout:

stderr:
- 11:42:53.447 INFO: /tmp/tmpd42j2lo8/query.a3m is in A2M, A3M or FASTA format

- 11:42:53.447 WARNING: Ignoring invalid symbol '*' at pos. 1623 in line 2 of /tmp/tmpd42j2lo8/query.a3m

- 11:42:53.610 ERROR: [subseq from] CRISPR-associated endonuclease Cas9/Csn1 n=212 Tax=root TaxID=1 RepID=CAS9_STRP1
- 11:42:53.610 ERROR: Error in /opt/conda/conda-bld/hhsuite_1616660820288/work/src/hhalignment.cpp:1244: Compress:

- 11:42:53.610 ERROR: sequences in /tmp/tmpd42j2lo8/query.a3m do not all have the same number of columns,

- 11:42:53.610 ERROR:
e.g. first sequence and sequence UniRef90_Q99ZW2/2-1048.

- 11:42:53.610 ERROR: Check input format for '-M a2m' option and consider using '-M first' or '-M 50'