galaxyproject / galaxyproject/tools-iuc

Request for some GATK tools to detect RNA-seq SNVs

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tool request
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HTML
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201
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Merged PRs (30d)
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Description

Hi, guys! I would really appreciate if you can add some of GATK tools needed to detect RNA-seq SNVs following the GATK best practices guideline here: https://gatk.broadinstitute.org/hc/en-us/articles/360035531192-RNAseq-short-variant-discovery-SNPs-Indels-

The tools are:
- SplitNCigarReads
- BaseRecalibration
- ApplyRecalibration
- AnalyzeCovariates
- HaplotypeCaller
- VariantFiltration

Contributor guide

Open the contributing guide

Research direction

Read the linked GATK RNA-seq short-variant discovery best-practices guideline and review the six requested tools: SplitNCigarReads, BaseRecalibration, ApplyRecalibration, AnalyzeCovariates, HaplotypeCaller, and VariantFiltration. The issue names no files or tests, so confirm the repository's wrapper conventions and scope before starting; done means the requested tools are added consistently with those conventions.

Written by the indexing model from the issue text.

Assessment

Domain
bioinformatics
Issue type
Feature
Difficulty
5/5
Estimated time
Over a week
Activity status
Stale
Clarity
Mostly clear
Newbie friendliness
30/100

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