galaxyproject / galaxyproject/tools-devteam

Unsorted BAM output for bwa mem?

Open
#478 2 comments 1 reaction 0 assignees View on GitHub
Dominant language
Python
Stars
37
Forks
94
PR merge metrics
No merged PRs in 30d

Description

We have a [HiC-related tool](https://github.com/maxplanck-ie/HiCExplorer) that's [available in Galaxy](https://toolshed.g2.bx.psu.edu/repository/browse_repositories?sort=name&operation=view_or_manage_repository&f-free-text-search=hicexplorer&id=f1554978eeb3da8b) that requires SAM/BAM input that is not coordinate sorted. As input, we normally use BAM files produced by bwa mem, which work well except for the fact that one needs to undo the coordinate sorting. Would people be open to me making a PR that adds a "do not sort the output BAM file" option? I would propose to hide this under a conditional (as is done with all of the "analysis_type" stuff currently) and have it default to "No", so people are less likely to accidentally select it.

This would save people time and disk space when doing this sort of analysis.

Contributor guide

Open the contributing guide

Assessment

This issue has not been assessed yet.

Get new issues in your inbox

A short digest of beginner-friendly GitHub issues.