forrtproject / forrtproject/fred-data

Review Fusobacterium protocol counted as original target and conflicting outcome codes

Open
#141 0 comments 0 reactions 0 assignees View on GitHub
Dominant language
HTML
Stars
1
Forks
0
PR merge metrics
No merged PRs in 30d

Description

The 14 September 2026 explorer snapshot links replication `10.7554/elife.25801` to both:

- `10.1101/gr.126516.111`, *Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma*: **mixed**.
- `10.7554/elife.10012`, *Registered report: Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma*: **failed**.

The [Registered Report PDF](https://cdn.elifesciences.org/elife-articles/10012/pdf/elife-10012.pdf) describes the plan to replicate Castellarin et al. The second relation appears to connect protocol and results, rather than a second original empirical finding. It risks inflating target/outcome counts and misrepresenting the protocol as a failed original.

Please verify relation types and the intended coding unit against the [replication report](https://doi.org/10.7554/elife.25801), reconcile mixed/failed labels, preserve protocol provenance separately where appropriate, and refresh downstream summaries. Do not deduplicate indiscriminately by replication DOI: legitimate reports can test multiple originals.

Contributor guide

No contributing guide indexed for this repository

Research direction

Start by comparing the replication report at 10.7554/elife.25801 with the Registered Report PDF for 10.7554/elife.10012 and the linked original at 10.1101/gr.126516.111. Trace how relation types and outcome codes feed downstream summaries; done means protocol provenance is distinct, mixed/failed labels are reconciled, and summaries are refreshed without collapsing legitimate multi-target reports.

Written by the indexing model from the issue text.

Assessment

Domain
data
Issue type
Bug
Difficulty
4/5
Estimated time
3-5 days
Activity status
Active
Clarity
Mostly clear
Newbie friendliness
45/100

Get new issues in your inbox

A short digest of beginner-friendly GitHub issues.