Upload fails with ESP32-S2 native USB

When trying to use esp-web.tools to upload to an esp32-s2 with its onboard usb, the upload fails.

On Windows (Chrome or Edge), I get the following error

ESP Web Tools 9.2.1 by Nabu Casa; https://esphome.github.io/esp-web-tools/
install-dialog-2aee1312.js:424 esptool.js
install-dialog-2aee1312.js:424 Serial port WebSerial VendorID 0x303a ProductID 0x2
install-dialog-2aee1312.js:424 Connecting...
install-dialog-2aee1312.js:424 .
install-dialog-2aee1312.js:424 Detecting chip type...
install-dialog-2aee1312.js:424 ESP32-S2
install-dialog-2aee1312.js:424 Chip is ESP32-S2FH32
install-dialog-2aee1312.js:424 Features: Wi-Fi,Embedded 4MB Flash
install-dialog-2aee1312.js:424 Crystal is 40MHz
install-dialog-2aee1312.js:424 MAC: 48:27:e2:57:7c:10
install-dialog-2aee1312.js:424 Uploading stub...
install-dialog-2aee1312.js:724 Error: Timeout
at ia.read (install-dialog-2aee1312.js:424:72641)
at async ta.command (install-dialog-2aee1312.js:424:55233)
at async ta.check_command (install-dialog-2aee1312.js:424:58833)
at async ta.mem_block (install-dialog-2aee1312.js:424:59483)
at async ta.run_stub (install-dialog-2aee1312.js:424:65415)
at async ta.main_fn (install-dialog-2aee1312.js:424:66917)
at async install-dialog-2aee1312.js:724:2934
(anonymous) @ install-dialog-2aee1312.js:724
await in (anonymous) (async)
_confirmInstall @ install-dialog-2aee1312.js:724
await in _confirmInstall (async)
handleEvent @ styles-e96248a3.js:1
install.openepaperlink.de/:1 Uncaught (in promise) DOMException: Failed to execute 'open' on 'SerialPort': Failed to open serial port.

And in 1 out of 10 times, the upload works, but only if i hold the GPIO 0 button. Uploading to ESP32 or Esp32-S3 works with no problems.

On Linux, I get this error:

ESP Web Tools 9.2.1 by Nabu Casa; https://esphome.github.io/esp-web-tools/
install-dialog-2aee1312.js:424 esptool.js
install-dialog-2aee1312.js:424 Serial port WebSerial VendorID 0x303a ProductID 0x2
install-dialog-2aee1312.js:424 Connecting...
install-dialog-2aee1312.js:424 .
install-dialog-2aee1312.js:424 .
install-dialog-2aee1312.js:424 .
install-dialog-2aee1312.js:424 .
install-dialog-2aee1312.js:424 .
install-dialog-2aee1312.js:424

install-dialog-2aee1312.js:424 Detecting chip type...
install-dialog-2aee1312.js:424 ESP32-S2
install-dialog-2aee1312.js:424 Chip is ESP32-S2FH32
install-dialog-2aee1312.js:424 Features: Wi-Fi,Embedded 4MB Flash
install-dialog-2aee1312.js:424 Crystal is 40MHz
install-dialog-2aee1312.js:424 MAC: 48:27:e2:57:7c:10
install-dialog-2aee1312.js:424 Uploading stub...
install-dialog-2aee1312.js:724 Error: Timeout
at ia.read (install-dialog-2aee1312.js:424:72641)
at async ta.command (install-dialog-2aee1312.js:424:55233)
at async ta.check_command (install-dialog-2aee1312.js:424:58833)
at async ta.mem_block (install-dialog-2aee1312.js:424:59483)
at async ta.run_stub (install-dialog-2aee1312.js:424:65415)
at async ta.main_fn (install-dialog-2aee1312.js:424:66917)
at async install-dialog-2aee1312.js:724:2934
(anonymous) @ install-dialog-2aee1312.js:724
await in (anonymous) (async)
_confirmInstall @ install-dialog-2aee1312.js:724
await in _confirmInstall (async)
handleEvent @ styles-e96248a3.js:1
install-dialog-2aee1312.js:424 esptool.js
install-dialog-2aee1312.js:424 Serial port WebSerial VendorID 0x303a ProductID 0x2
install-dialog-2aee1312.js:424 Connecting...
install-dialog-2aee1312.js:724 DOMException: Failed to execute 'setSignals' on 'SerialPort': Failed to set control signals.
(anonymous) @ install-dialog-2aee1312.js:724
await in (anonymous) (async)
_confirmInstall @ install-dialog-2aee1312.js:724
await in _confirmInstall (async)
handleEvent @ styles-e96248a3.js:1
install-dialog-2aee1312.js:724 Uncaught (in promise) DOMException: Failed to execute 'setSignals' on 'SerialPort': Failed to set control signals.
await (async)
_confirmInstall @ install-dialog-2aee1312.js:724
await in _confirmInstall (async)
handleEvent @ styles-e96248a3.js:1
install-dialog-2aee1312.js:724 Uncaught (in promise) DOMException: Failed to execute 'open' on 'SerialPort': The port is already open.
at https://install.openepaperlink.de/js/install-dialog-2aee1312.js:724:5560

Is this an issue of esptool-js ?