epam / epam/ketcher

Macro: Obtain sequence for modified chains

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Epic: Sequence representation
Dominant language
TypeScript
Stars
884
Forks
262
Avg merge
3d 10h
Merged PRs (30d)
126

Description

**Background**
Users need to be able to see the unmodified, natural sequence of a modified nucleotide. That way they can search for the unmodified sequence to find all the modified forms.
The same rule could be applied also for peptide sequences.

**Requirements**
1. User should be able to save modified chain as sequence made up from natural analogs of monomers.
2. For RNA: phosphates and sugars that are not a part of nucleotide or nucleoside are not exported.
3. Chems are not exported.
Examples:
- Peptide

Sequence: ARGFCKAEDA
- RNA

Sequence: TCA

Contributor guide

No contributing guide indexed for this repository

Research direction

No files, tests, or entry points are named in the issue. Start by locating the code that exports modified peptide and RNA chains as sequences, then trace how monomers, phosphates, sugars, and chems are represented. Done means natural analog sequences match the peptide and RNA examples while excluding the specified non-exported components.

Written by the indexing model from the issue text.

Assessment

Tech stack
typescript
Domain
bioinformatics
Issue type
Feature
Difficulty
5/5
Estimated time
Over a week
Activity status
Stale
Clarity
Mostly clear
Newbie friendliness
25/100

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