Server 500 Error COnn Close, Jersey 200 OK

Continuously and absolute randomly receiving Internal server erro 500 while all code executing perfectly, logs show that method called was proper, all code executed and results returned in desired manner.

On top of all after going through Jersey "Monitoring Statistics as MBeans" the last method return code is 200 but Rest client always show 500.

Noticeable thing is that unlimited times first time 500 error come and then every thing goes fine on second time, and usually always 500 error come until i make some irrelevant change in code and redeploy.
#### Environment
Windows 7 Local Machine, Linux on AWS Virtual Server
Tomcat 8.0.36, Tomcat 9.0, Jetty 9.3.11.v20160721
#### Affected Versions
[2.23]