deepcelllineage / deepcelllineage/mitolin

Generate a text file with cytochrome b function and pathway attributes

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Description

## Aim

Generate a text file for mitochondrial gene cytochrome b that holds information relevant to its function.

## Background

The initial aim of the DCL project is to use variation in the mitochondrial genome to determine relationships between cells. Variation at some locations will be more frequent than variation at other locations. Knowing why will help us understand the role these variants play in cellular fitness.

Understanding the products of mitochondrial DNA will help us make better sense of variation between mitochondrial DNA of individual cells.

Cytochrome b is a protein found in the mitochondria of eukaryotic cells. It functions as part of the electron transport chain and is the main subunit of transmembrane cytochrome bc1 and b6f complexes. See [Cytochrome b Wikipedia page](https://en.wikipedia.org/wiki/Cytochrome_b) for more details.

## Method

Start by skim reading the [Gene Ontology section of the Biostar Handbook](https://www.biostarhandbook.com/gene-ontology.html).

- For biostar book login details, look at the pinned items in our Slack channel #deepcelllineage. Not a member yet? [Join our Slack workspace](http://bit.ly/JoinSlackFastaiSFbay).

## Document your work

Please fork & clone this repo. Check out a branch for your work, then push and make a PR for us to merge your note and files.

Add a note (can be .md or .ipynb) with your steps in [mitolin/nb](https://github.com/deepcelllineage/mitolin/tree/master/nb).

Your note should be named as follows:

- DATE-issue#-shortdescription.ext

e.g.:

- 20190701-i10-cb-function-txt.md

## Questions?

Please put questions related to this issue in this issue thread.

If you want a quick response, post a link to your comment in this thread to Slack #deepcelllineage and tag @Deena or others. You can also DM @Deena.

To join Slack enter your email address [here](http://bit.ly/JoinSlackFastaiSFbay). For questions NOT specifically related to this issue, get in touch through any of the communication methods listed in [DCL's overview README](https://github.com/deepcelllineage/overview/blob/master/README.md).

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