cucapra / cucapra/pollen

Pangenotype matrix: end-to-end GWAS regression demo

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Dominant language
Rust
Stars
45
Forks
3
PR merge metrics
No merged PRs in 30d

Description

Starting with the current matrix.py demo from #238, let's add on NumPy-based regression to perform a sort of minimal GWAS experiment. This will probably need to happen after #245 to avoid a bunch of churn.

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First steps

  1. Read the whole issue, then the project's contributing guide.
  2. Comment on the issue to say you are picking it up — it saves two people doing the same work.
  3. Fork the repository and make your change on a branch.
  4. Open a pull request that references the issue number.

Research direction

Start with flatgfa-py/examples/matrix.py, the current demo referenced from #238, and review #245 before making plans because this work is expected to follow it. Trace how the matrix demo runs, then determine the scope needed for a NumPy-based regression and a minimal end-to-end GWAS experiment; done should be a runnable regression demo.

Written by the indexing model from the issue text.

Assessment

Tech stack
numpy, python
Domain
bioinformatics, data
Issue type
Feature
Difficulty
5/5
Estimated time
Over a week
Activity status
Stale
Clarity
Needs clarification
Newbie friendliness
35/100

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