cfe-lab / cfe-lab/MiCall

Add sanity check for reference sequences

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#87 0 comments 0 reactions 0 assignees View on GitHub

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enhancement
Dominant language
Python
Stars
21
Forks
11
Avg merge
12h 5m
Merged PRs (30d)
24

Description

We've been surprised to find strange characters in our reference sequences, and they have caused issues like #86. We should add some level of sanity check on the scripts that first use our reference sequences to confirm that they only contain the expected letters.
To start with, do a manual review of the reference sequences and clean out unexpected characters.

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First steps

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  3. Fork the repository and make your change on a branch.
  4. Open a pull request that references the issue number.

Research direction

Review the reference sequences and identify the scripts that first use them. Check the sequences for characters outside the expected alphabet, remove unexpected characters, and add the requested sanity check so invalid reference data is detected.

Written by the indexing model from the issue text.

Assessment

Tech stack
python
Domain
bioinformatics
Issue type
Feature
Difficulty
3/5
Estimated time
1-2 days
Activity status
Stale
Clarity
Mostly clear
Newbie friendliness
45/100

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