cfe-lab / cfe-lab/MiCall

Add coverage plots and scores for non-coding regions

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Dominant language
Python
Stars
21
Forks
11
Avg merge
12h 5m
Merged PRs (30d)
24

Description

Issue #589 added non-coding regions to nuc.csv counts, but didn't include them in coverage plots or coverage_scores.csv. That means that they won't be visible from QAI's micall pages. If that frustrates users, then add plots and scores.

  • Decide how to score coverage. Are there key positions?
  • Add a new version of the coverage maps that uses nucleotide positions instead of amino acid positions.

Contributor guide

No contributing guide indexed for this repository

First steps

  1. Read the whole issue, then the project's contributing guide.
  2. Comment on the issue to say you are picking it up — it saves two people doing the same work.
  3. Fork the repository and make your change on a branch.
  4. Open a pull request that references the issue number.

Research direction

Start by reviewing issue #589 and the existing handling of non-coding regions in nuc.csv, then inspect how coverage plots and coverage_scores.csv feed MiCall pages. Decide which nucleotide positions matter for scoring and define the coverage-map version using nucleotide rather than amino-acid positions. Done means non-coding regions appear in the plots and receive documented coverage scores.

Written by the indexing model from the issue text.

Assessment

Tech stack
python
Domain
bioinformatics
Issue type
Feature
Difficulty
5/5
Estimated time
Over a week
Activity status
Stale
Clarity
Needs clarification
Newbie friendliness
25/100

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