Low-prevalance nucleotide mutations
Open
Nobody has claimed this yet.
- Dominant language
- Python
- Stars
- 21
- Forks
- 11
- Avg merge
- 12h 5m
- Merged PRs (30d)
- 24
Description
Follow up from #588: we should review the low-prevalence mutations to make sure they are real and not caused by alignment problems. For example, ORF1ab positions 12405 and 12406 in COVID222NT.
Contributor guide
No contributing guide indexed for this repository
First steps
- Read the whole issue, then the project's contributing guide.
- Comment on the issue to say you are picking it up — it saves two people doing the same work.
- Fork the repository and make your change on a branch.
- Open a pull request that references the issue number.
Research direction
Begin by reading the follow-up issue #588 and examining the COVID222NT example, focusing on ORF1ab positions 12405 and 12406. The issue mentions no files, tests, or entry points; done means determining whether the low-prevalence mutations are real or alignment artifacts.
Written by the indexing model from the issue text.
Assessment
- Tech stack
- python
- Domain
- bioinformatics
- Issue type
- Bug
- Difficulty
- 5/5
- Estimated time
- Over a week
- Activity status
- Stale
- Clarity
- Needs clarification
- Newbie friendliness
- 25/100