Get key positions from resistance rules
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- Dominant language
- Python
- Stars
- 21
- Forks
- 11
- Avg merge
- 12h 5m
- Merged PRs (30d)
- 24
Description
Since we added rules for scoring the resistance to HIV and HCV drugs, we could use the mutation positions to choose key positions when giving a coverage score. Presumably, we should continue to allow key positions as part of the project definitions for regions that don't have resistance rules.
Somewhat related to the tool for editing project definitions described in #425.
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First steps
- Read the whole issue, then the project's contributing guide.
- Comment on the issue to say you are picking it up — it saves two people doing the same work.
- Fork the repository and make your change on a branch.
- Open a pull request that references the issue number.
Research direction
Start by reviewing the existing resistance-rule scoring and project-definition handling, then read the related project-definition editor discussion in #425. The intended result is for mutation positions from resistance rules to determine key positions for coverage scoring while preserving explicitly configured key positions where no rules exist.
Written by the indexing model from the issue text.
Assessment
- Tech stack
- python
- Domain
- bioinformatics
- Issue type
- Feature
- Difficulty
- 5/5
- Estimated time
- Over a week
- Activity status
- Stale
- Clarity
- Mostly clear
- Newbie friendliness
- 30/100