cfe-lab / cfe-lab/MiCall

Separate HCV 1A from other subtypes

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enhancement
Dominant language
Python
Stars
21
Forks
11
Avg merge
12h 5m
Merged PRs (30d)
24

Description

Currently, we split genotype 1 into 1A and 1B, where all other subtypes are reported as 1A. Chanson asked that we split them into 1A, 1B, and 1. 1A and 1 will have the same resistance interpretations, but physicians will treat them differently.

I suggest we configure a list of genotypes for each rule set, so we don't have to create duplicate rules for 1A and 1.

Do this after validating against the current HCV reports, because they only report 1A and 1B.

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Research direction

Start by validating the current HCV reports, since they only report 1A and 1B. Then inspect the genotype and rule-set configuration entry points to determine how 1A, 1B, and 1 are represented. Done means the three genotypes are reported distinctly, 1A and 1 share resistance interpretations without duplicate rules, and existing reports remain valid.

Written by the indexing model from the issue text.

Assessment

Tech stack
python
Domain
bioinformatics
Issue type
Feature
Difficulty
4/5
Estimated time
3-5 days
Activity status
Stale
Clarity
Mostly clear
Newbie friendliness
38/100

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