cfe-lab / cfe-lab/MiCall

Move Virco report into MiCall pipeline

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enhancement
Dominant language
Python
Stars
21
Forks
11
Avg merge
12h 5m
Merged PRs (30d)
24

Description

Convert the Virco scoring algorithm to use the Stanford ASI rules format, and place it under internal source control.

The current algorithm is implemented here:

  • fdrive/RESIST/ruby/ckwlib/virco_algorithm.rb

The driver script is fdrive/RESIST/MISEQ/miseq_gen_results.rb.

  • convert rules
  • compare results to Ruby version
  • move key coverage positions into scoring algorithm (separate issue?)

Contributor guide

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First steps

  1. Read the whole issue, then the project's contributing guide.
  2. Comment on the issue to say you are picking it up — it saves two people doing the same work.
  3. Fork the repository and make your change on a branch.
  4. Open a pull request that references the issue number.

Research direction

Start by reading fdrive/RESIST/ruby/ckwlib/virco_algorithm.rb and the driver fdrive/RESIST/MISEQ/miseq_gen_results.rb to understand the current scoring flow. Convert the rules to Stanford ASI format, compare results with the Ruby implementation, and verify whether key coverage positions belong in this work; done means the converted algorithm is under internal source control and the checklist is resolved.

Written by the indexing model from the issue text.

Assessment

Tech stack
ruby
Domain
bioinformatics
Issue type
Feature
Difficulty
4/5
Estimated time
3-5 days
Activity status
Stale
Clarity
Mostly clear
Newbie friendliness
35/100

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