Impurity in clonal samples
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question
- Dominant language
- Python
- Stars
- 21
- Forks
- 11
- Avg merge
- 12h 5m
- Merged PRs (30d)
- 24
Description
On the run from 3 Jul 2015, one of the pure clonal samples seemed to have a mixture at one position. Chanson will send a report that shows where the mixture is. Try to see if there really is a mixture there or if there's a problem with the analysis.
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First steps
- Read the whole issue, then the project's contributing guide.
- Comment on the issue to say you are picking it up — it saves two people doing the same work.
- Fork the repository and make your change on a branch.
- Open a pull request that references the issue number.
Research direction
Start by obtaining Chanson's report identifying the mixed position in the pure clonal sample from the 3 Jul 2015 run. Reproduce or inspect the pipeline analysis for that sample, then compare the result with the report; the work is done when the mixture is shown to be genuine or attributed to an analysis problem.
Written by the indexing model from the issue text.
Assessment
- Tech stack
- python
- Domain
- bioinformatics
- Issue type
- Bug
- Difficulty
- 4/5
- Estimated time
- 3-5 days
- Activity status
- Stale
- Clarity
- Needs clarification
- Newbie friendliness
- 25/100