biocore / biocore/microprot

calculate effective family size for MSA_ripe rule

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#26 11 comments 0 reactions 1 assignee Claimed by @qiyunzhu View on GitHub
finishing touches version 3
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Python
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Description

the script should live in: `scripts/calculate_Neff.py`
Once HHblits is completed we need to calculate the effective family size from `a3m` file.

N_eff = N_clu(%) / sqrt(N_aa)

depending on N_eff and length of the protein the script should make a decision if the MSA is "ripe" for Rosetta predictions, or "not_ripe".

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