SciML / SciML/Optimization.jl

Enhanced Scatter Search

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Dominant language
Julia
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839
Forks
100
Avg merge
20h 43m
Merged PRs (30d)
38

Description

What kind of problems is it mostly used for? Please describe.

Enhanced Scatter Search (eSS) is a metaheuristic used in optimisation of large ODE models cellular signalling networks. It is currently used in the R package CellNopt, where it is mainly used for parameter estimation of the ODE-variant of the logic signalling models.

Describe the algorithm you’d like

The algorithm as implemented in C or the AMIGO2 toolbox. The repository of the C implementation includes a description of the algorithm.

Other implementations to know about

The algorithm is currently implemented in C (https://github.com/amirmasoudabdol/eSS) and part of the AMIGO2 toolbox (https://sites.google.com/site/amigo2toolbox).

References

  1. Rodriguez-Fernandez, M., Egea, J. a, & Banga, J. R. (2006). Novel metaheuristic for parameter estimation in nonlinear dynamic biological systems. BMC Bioinformatics, 7, 483. doi:10.1186/1471-2105-7-483
  2. Egea, J. a., Martí, R., & Banga, J. R. (2010). An evolutionary method for complex-process optimization. Computers & Operations Research, 37(2), 315–324. doi:10.1016/j.cor.2009.05.003

Contributor guide

Open the contributing guide

First steps

  1. Read the whole issue, then the project's contributing guide.
  2. Comment on the issue to say you are picking it up — it saves two people doing the same work.
  3. Fork the repository and make your change on a branch.
  4. Open a pull request that references the issue number.

Research direction

Start by reviewing the referenced C implementation of Enhanced Scatter Search and its implementation in the AMIGO2 toolbox, then identify where a Julia version would fit in Optimization.jl. Done means a Julia implementation of the described eSS algorithm that supports the optimization use cases outlined in the issue.

Written by the indexing model from the issue text.

Assessment

Tech stack
julia
Domain
backend
Issue type
Feature
Difficulty
5/5
Estimated time
Over a week
Activity status
Stale
Clarity
Needs clarification
Newbie friendliness
25/100

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