Investigate Metadome

Peer says:

We use the [Metadome](https://stuart.radboudumc.nl/metadome/) web app for regional constraints within genes all the time in research and diagnostics. Now the data has become available, is that something you could add to VG?
Or is that something that should be included earlier in the pipeline?

Data is available:

https://zenodo.org/record/6625251#.YqHL5BbSWEc

Data looks like:

```
chrom,pos_start,pos_stop,strand,symbol,gencode_transcription_id,sw_dn_ds,sw_coverage,sw_size,domain_id,consensus_pos
chr19,10781282,10781284,+,ILF3,ENST00000420083.1,0.1875,0.5238095238095238,10,,
chr19,10781650,10781652,+,ILF3,ENST00000420083.1,0.2005813953488372,0.5714285714285714,10,,
chr19,10781653,10781655,+,ILF3,ENST00000420083.1,0.1914893617021277,0.6190476190476191,10,,
chr19,10781656,10781658,+,ILF3,ENST00000420083.1,0.162,0.6666666666666666,10,,
chr19,10781659,10781661,+,ILF3,ENST00000420083.1,0.14862385321100918,0.7142857142857143,10,,
chr19,10781662,10781664,+,ILF3,ENST00000420083.1,0.13043478260869565,0.7619047619047619,10,,
chr19,10781665,10781667,+,ILF3,ENST00000420083.1,0.10889929742388757,0.8095238095238095,10,,
```

The transcripts per gene looks like:

```
count 18541.000000
mean 2.252953
std 1.726056
min 1.000000
25% 1.000000
50% 2.000000
75% 3.000000
max 30.000000
```

And it's all Ensembl