RosettaCommons / RosettaCommons/foundry
How to generation many seq in one backbone
Open
Nobody has claimed this yet.
- Dominant language
- Python
- Stars
- 966
- Forks
- 181
- Avg merge
- 4d 4h
- Merged PRs (30d)
- 2
Description
hello,
nice work.
when i use it to design protein binder, I find it had generate sequence not GGGG...... Is it necessary to continue executing ProteinMPNN for sequence generation as well as structure prediction using RF3?
Contributor guide
First steps
- Read the whole issue, then the project's contributing guide.
- Comment on the issue to say you are picking it up — it saves two people doing the same work.
- Fork the repository and make your change on a branch.
- Open a pull request that references the issue number.
Research direction
Start by reviewing the repository's entry points and usage guidance for ProteinMPNN and RF3, since the issue does not name a file or test. Determine whether the binder workflow requires both models for sequence generation and structure prediction, then document the supported sequence-generation workflow and expected output.
Written by the indexing model from the issue text.
Assessment
- Tech stack
- python
- Domain
- machine-learning
- Issue type
- Documentation
- Difficulty
- 4/5
- Estimated time
- 3-5 days
- Activity status
- Stale
- Clarity
- Needs clarification
- Newbie friendliness
- 25/100