RosettaCommons / RosettaCommons/documentation

From Mantis: 0000008: Explicit hydrogens and documentation for molfile_to_params.py

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Description

The documentation does not point out that the molfile which is the input to molfile_to_params.py must already contain explicit hydrogens. (Unlike standard PDB inputs to Rosetta, which can be provided as heavy-atom only.)

Not having hydrogens on the input molfile means that the energies and binding positions in fullatom mode with the thus-generated params file will not be correct.

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  3. Fork the repository and make your change on a branch.
  4. Open a pull request that references the issue number.

Research direction

Start by locating the documentation for molfile_to_params.py and review how its input requirements are described. Update it to state that the input molfile must contain explicit hydrogens, contrasting this with heavy-atom-only standard PDB inputs; done when the fullatom-mode warning is clear.

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Assessment

Tech stack
python
Domain
documentation
Issue type
Documentation
Difficulty
2/5
Estimated time
1-3 hours
Activity status
Stale
Clarity
Mostly clear
Newbie friendliness
45/100

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