RosettaCommons / RosettaCommons/RFdiffusion
Succes rate
Open
Nobody has claimed this yet.
- Dominant language
- Python
- Stars
- 3.1k
- Forks
- 644
- PR merge metrics
- No merged PRs in 30d
Description
Is there any proof that using hotsposts is better than unconditional design. I assume that if hotsposts are well selected it can be better, but when you have no clear idea of the mechanism of a protein, do you think is better to run unconditional design. Looking forward to read your opinions.
Contributor guide
No contributing guide indexed for this repository
First steps
- Read the whole issue, then the project's contributing guide.
- Comment on the issue to say you are picking it up — it saves two people doing the same work.
- Fork the repository and make your change on a branch.
- Open a pull request that references the issue number.
Research direction
No files, tests, or entry points are identified. First clarify whether this is requesting a code or documentation change, then define how hotspot-guided and unconditional design should be compared and what evidence would count as success.
Written by the indexing model from the issue text.
Assessment
- Tech stack
- python
- Domain
- bioinformatics, machine-learning
- Issue type
- Feature
- Difficulty
- 5/5
- Estimated time
- Over a week
- Activity status
- Quiet
- Clarity
- Needs clarification
- Newbie friendliness
- 20/100