RosettaCommons / RosettaCommons/RFdiffusion
Modifying Binder Length when using fold conditioning
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- Python
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Description
Hi @joewatchwell ,
I noticed that when fold conditioning is used to create a secondary structure and adjacency matrix that the binder length is based on the size of the 1st dimension / length of the ss. Is it possible to alter the binder length when using a secondary structure and adjacency matrix on our target, or will we have to crop out target further? Thanks!
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Research direction
The issue names no files or tests; start by tracing the fold-conditioning input path and how the secondary-structure length sets binder length. Determine whether an independent binder-length setting is feasible, and define the expected behavior for mismatched lengths before implementation or documentation.
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Assessment
- Tech stack
- python
- Domain
- bioinformatics, machine-learning
- Issue type
- Feature
- Difficulty
- 5/5
- Estimated time
- Over a week
- Activity status
- Stale
- Clarity
- Needs clarification
- Newbie friendliness
- 25/100