RosettaCommons / RosettaCommons/PyRosetta.notebooks
Why the mutation can not be executed thoroughly?
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- Dominant language
- Jupyter Notebook
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Description
when I use pyrosetta to convert protein amino acid, there is some amino acid keep their original state, some others converted as I commanded.
The function I used is MutateResidue(). As the picture below, the LEU is a converted AA from ASN, but there is still one ASN cannot to be concerted into LEU.
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Research direction
The report only identifies PyRosetta's MutateResidue() function and an attached image; it does not name a notebook, test, or reproducible input. Start by reproducing the mutation with the reported amino-acid structure, then determine the conditions under which every intended ASN residue is converted and document a verified result.
Written by the indexing model from the issue text.
Assessment
- Tech stack
- jupyter-notebook, python
- Domain
- bioinformatics
- Issue type
- Bug
- Difficulty
- 4/5
- Estimated time
- 3-5 days
- Activity status
- Stale
- Clarity
- Needs clarification
- Newbie friendliness
- 32/100