OpenFreeEnergy / OpenFreeEnergy/openfe

Predefined solvent component

Open
#661 4 comments 0 reactions 0 assignees View on GitHub

Nobody has claimed this yet.

Dominant language
Python
Stars
331
Forks
56
Avg merge
3d 9h
Merged PRs (30d)
13

Description

I wonder if there is a way to generate a SolventComponent from a predefined structure? A use case might be a system with crystalographic waters, crystalographic ions, and cofactors, or a membrane protein.

Contributor guide

Open the contributing guide

First steps

  1. Read the whole issue, then the project's contributing guide.
  2. Comment on the issue to say you are picking it up — it saves two people doing the same work.
  3. Fork the repository and make your change on a branch.
  4. Open a pull request that references the issue number.

Research direction

Start by locating the SolventComponent implementation and the existing structure or component construction entry points. Determine how predefined structures should represent crystallographic waters, ions, cofactors, or membrane proteins, then define the expected behavior and tests for creating a SolventComponent from them.

Written by the indexing model from the issue text.

Assessment

Tech stack
python
Domain
backend
Issue type
Feature
Difficulty
5/5
Estimated time
Over a week
Activity status
Stale
Clarity
Needs clarification
Newbie friendliness
25/100

Get new issues in your inbox

A short digest of beginner-friendly GitHub issues.