OpenFreeEnergy / OpenFreeEnergy/openfe

Benchmarking of HFE simulations

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Dominant language
Python
Stars
331
Forks
56
Avg merge
3d 9h
Merged PRs (30d)
13

Description

We have an HFE protocol, we should benchmark it and make some pretty plots.

Currently WIP:

  • QA data from Mike needs to be analyzed
  • Alchemiscale-generated runs of the freesolv subset is in progress (with the charge fix)

Contributor guide

Open the contributing guide

First steps

  1. Read the whole issue, then the project's contributing guide.
  2. Comment on the issue to say you are picking it up — it saves two people doing the same work.
  3. Fork the repository and make your change on a branch.
  4. Open a pull request that references the issue number.

Research direction

Start by analyzing the QA data from Mike and the Alchemiscale-generated FreeSolv subset once the charge-fix runs finish. Produce benchmark results and plots for the HFE protocol, with the analysis and visualization work complete for both data sources.

Written by the indexing model from the issue text.

Assessment

Tech stack
python
Domain
data-visualization, performance
Issue type
Feature
Difficulty
4/5
Estimated time
3-5 days
Activity status
Stale
Clarity
Needs clarification
Newbie friendliness
25/100

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