OpenFreeEnergy / OpenFreeEnergy/openfe

Add plots of DG for each state to the protocol results

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Dominant language
Python
Stars
331
Forks
56
Avg merge
3d 9h
Merged PRs (30d)
13

Description

When investigating problems in simulations (e.g. large standard deviation across repeats) it can be very helpful to look at the contribution of DG from the different lambda windows to help narrow down where the sampling problem might be.
See e.g. this plot. The different estimators may not be necessary.

Image

Contributor guide

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First steps

  1. Read the whole issue, then the project's contributing guide.
  2. Comment on the issue to say you are picking it up — it saves two people doing the same work.
  3. Fork the repository and make your change on a branch.
  4. Open a pull request that references the issue number.

Research direction

Start by locating the code that generates protocol results and any existing result plots, then compare the requested output with the linked example image. Done means protocol results include plots showing DG contributions for each state or lambda window, with optional estimator plots only if they are needed.

Written by the indexing model from the issue text.

Assessment

Tech stack
python
Domain
data-visualization
Issue type
Feature
Difficulty
3/5
Estimated time
1-2 days
Activity status
Stale
Clarity
Mostly clear
Newbie friendliness
45/100

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