OpenFreeEnergy / OpenFreeEnergy/feflow

Integrate REST capable HTF from perses into FEflow

Open
#8 1 comment 0 reactions 0 assignees View on GitHub

Nobody has claimed this yet.

Dominant language
Python
Stars
20
Forks
4
PR merge metrics
No merged PRs in 30d

Description

We need to integrate the REST HTF object into feflow such that it can be used by the current protocols.

This implies reviewing the settings and probably refactoring the different HTFs (HybridTopologyFactory and RESTCapableTopologyFactory) in a more factory-method pattern.

The current implementation lives in https://github.com/choderalab/perses/blob/7eaa1626c7c935f9cc4156f9a53ced3694b40bf0/perses/annihilation/relative.py#L2701

Contributor guide

No contributing guide indexed for this repository

First steps

  1. Read the whole issue, then the project's contributing guide.
  2. Comment on the issue to say you are picking it up — it saves two people doing the same work.
  3. Fork the repository and make your change on a branch.
  4. Open a pull request that references the issue number.

Research direction

Start by reviewing the RESTCapableTopologyFactory implementation in perses/annihilation/relative.py around line 2701, then inspect feflow’s settings and current protocols. Determine how HybridTopologyFactory and RESTCapableTopologyFactory should fit a factory-method pattern; done means the REST HTF can be used by the current protocols.

Written by the indexing model from the issue text.

Assessment

Tech stack
python
Domain
tooling
Issue type
Feature
Difficulty
4/5
Estimated time
3-5 days
Activity status
Stale
Clarity
Needs clarification
Newbie friendliness
28/100

Get new issues in your inbox

A short digest of beginner-friendly GitHub issues.