a question regarding the temperature parameter
Nobody has claimed this yet.
- Dominant language
- Jupyter Notebook
- Stars
- 17
- Forks
- 15
- PR merge metrics
- No merged PRs in 30d
Description
Hi @prihoda ,
Thanks heaps for developing such an invaluable tool for the community.
When mRNAid calls RNAfold, does it use the default temperature? If I am gonna use mRNAid to design vaccine mRNA, do I have to select a specific temperature?
Thanks a lot in advance and I look forward to hearing from you.
Best Regards,
Huanle
Contributor guide
No contributing guide indexed for this repository
First steps
- Read the whole issue, then the project's contributing guide.
- Comment on the issue to say you are picking it up — it saves two people doing the same work.
- Fork the repository and make your change on a branch.
- Open a pull request that references the issue number.
Research direction
Review the mRNAid integration with RNAfold, focusing on how the temperature parameter is handled. Determine whether RNAfold's default temperature is used and what guidance is appropriate for vaccine mRNA design; the issue is resolved when this behavior and guidance are clearly answered.
Written by the indexing model from the issue text.
Assessment
- Tech stack
- jupyter-notebook
- Domain
- bioinformatics
- Issue type
- Documentation
- Difficulty
- 2/5
- Estimated time
- 1-3 hours
- Activity status
- Stale
- Clarity
- Needs clarification
- Newbie friendliness
- 25/100