Merck / Merck/BioPhi

OASis prevalence threshold for custom

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Dominant language
Python
Stars
265
Forks
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Description

Currently, OASis prevalence threshold settings:
loose (≥1% subjects)
relaxed (≥10% subjects)
medium (≥50% subjects)
strict (≥90% subjects)
custom

When I set a 5% as custom threshold, the threshold field in the output xlsx file is strict, rather than loose.
I tried other values, rather than 1,10,50,90, all threshold field in the output xlsx file is strict.
Could someone explain this for me?

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First steps

  1. Read the whole issue, then the project's contributing guide.
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  3. Fork the repository and make your change on a branch.
  4. Open a pull request that references the issue number.

Research direction

Start by reproducing the issue with a custom OASis prevalence threshold such as 5% and inspect how the threshold is represented in the output XLSX file. Trace the threshold handling and output generation to determine why nonstandard values are labeled strict; done means custom values are reported correctly.

Written by the indexing model from the issue text.

Assessment

Tech stack
python
Domain
bioinformatics
Issue type
Bug
Difficulty
3/5
Estimated time
1-2 days
Activity status
Quiet
Clarity
Mostly clear
Newbie friendliness
48/100

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