Merck / Merck/BioPhi

Control number of mutations when humanizing

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Dominant language
Python
Stars
265
Forks
65
PR merge metrics
No merged PRs in 30d

Description

Hello, I tried multiple options, but regardless of number of iterations or limit parameter I am getting always the same number of mutations introduced. Humanness score indeed increases, but I would like to know if there is an option to say how many mutations I want to be introduced?

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First steps

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Research direction

The issue mentions humanization, iteration count, and the limit parameter but names no files or tests. Start by locating the humanization entry point and how those options are interpreted, then reproduce the unchanged mutation count. Done means an option reliably controls the requested number of introduced mutations and the behavior is covered by a regression test.

Written by the indexing model from the issue text.

Assessment

Tech stack
python
Domain
bioinformatics
Issue type
Feature
Difficulty
4/5
Estimated time
3-5 days
Activity status
Stale
Clarity
Needs clarification
Newbie friendliness
25/100

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