Merck / Merck/BioPhi

Enable generating multiple humanized sequence variants at once

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enhancement
Dominant language
Python
Stars
265
Forks
65
PR merge metrics
No merged PRs in 30d

Description

E.g. Sapiens*1-*5 + Vernier CDR graft + Vernier CDR graft with 1 Sapiens iteration

Contributor guide

No contributing guide indexed for this repository

First steps

  1. Read the whole issue, then the project's contributing guide.
  2. Comment on the issue to say you are picking it up — it saves two people doing the same work.
  3. Fork the repository and make your change on a branch.
  4. Open a pull request that references the issue number.

Research direction

Start by locating the current humanization entry points for Sapiens and Vernier CDR graft in BioPhi. Use the requested examples to clarify how multiple variants and iteration counts should be represented; done means the platform can generate the specified variants together with distinguishable results.

Written by the indexing model from the issue text.

Assessment

Tech stack
python
Domain
bioinformatics
Issue type
Feature
Difficulty
5/5
Estimated time
Over a week
Activity status
Stale
Clarity
Needs clarification
Newbie friendliness
25/100

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