KavrakiLab / KavrakiLab/APE-Gen
Failing to model some epitopes
- Dominant language
- Python
- Stars
- 4
- Forks
- 2
- PR merge metrics
- No merged PRs in 30d
Description
Hi all,
I'm modeling a set of epitopes (300.000) with APE-Gen and I got some errors in the process. I already modeled almost 100.000 epitopes and I got about 4% of errors (epitopes were not modeled). I made a loop to retry 5 times before jump to the next model. I'm attaching the list of epitopes and their respective HLAs. I hope you can find it useful in case you need to update the tool.
@jayveeabella @Dinler
[fail_epitopes_list.txt](https://github.com/KavrakiLab/APE-Gen/files/5235511/fail_epitopes_list.txt)
Contributor guide
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Research direction
Start with the attached fail_epitopes_list.txt and reproduce the reported APE-Gen failures using the listed epitopes and HLAs. Compare failed entries with successful models to identify a reproducible cause; done means the failures are explained or APE-Gen handles the affected inputs.
Written by the indexing model from the issue text.
Assessment
- Tech stack
- python
- Domain
- bioinformatics
- Issue type
- Bug
- Difficulty
- 4/5
- Estimated time
- 3-5 days
- Activity status
- Stale
- Clarity
- Needs clarification
- Newbie friendliness
- 35/100