KavrakiLab / KavrakiLab/APE-Gen

Failing to model some epitopes

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Dominant language
Python
Stars
4
Forks
2
PR merge metrics
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Description

Hi all,

I'm modeling a set of epitopes (300.000) with APE-Gen and I got some errors in the process. I already modeled almost 100.000 epitopes and I got about 4% of errors (epitopes were not modeled). I made a loop to retry 5 times before jump to the next model. I'm attaching the list of epitopes and their respective HLAs. I hope you can find it useful in case you need to update the tool.
@jayveeabella @Dinler

[fail_epitopes_list.txt](https://github.com/KavrakiLab/APE-Gen/files/5235511/fail_epitopes_list.txt)

Contributor guide

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Research direction

Start with the attached fail_epitopes_list.txt and reproduce the reported APE-Gen failures using the listed epitopes and HLAs. Compare failed entries with successful models to identify a reproducible cause; done means the failures are explained or APE-Gen handles the affected inputs.

Written by the indexing model from the issue text.

Assessment

Tech stack
python
Domain
bioinformatics
Issue type
Bug
Difficulty
4/5
Estimated time
3-5 days
Activity status
Stale
Clarity
Needs clarification
Newbie friendliness
35/100

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