Unable to run Dr Memory on Windows 10 64 bit version 1903

I download build 18083 from here: https://github.com/DynamoRIO/drmemory/releases

https://github.com/DynamoRIO/drmemory/releases/download/cronbuild-2.2.18083/DrMemory-Windows-2.2.18083-1.zip

I am running Windows 10 64-bit version 1903. If I try and run an application under DrMemory (even from an administrator window), I see the following output (after I exit the application again). There is no resfile in the logs directory.

DrMemory used to work on Windows with this application.

[f:\drmemory22\bin64] drmemory.exe c:\Perforce\client3\main\petro-sim\Petro-SIM.
exe
~~Dr.M~~ WARNING: unable to locate results file: can't open F:\DrMemory22\drmemo
ry\logs/resfile.5892 (code=2).
Dr. Memory failed to start the target application, perhaps due to
interference from invasive security software.
Try disabling other software or running in a virtual machine.
WARNING: Examine the following unusual libraries in this process to help identify
invasive software that may have affected the target application:

C:\WINDOWS\system32\WRusr.dll
C:\WINDOWS\SYSTEM32\MSIMG32.dll
C:\WINDOWS\System32\UMPDC.dll
C:\WINDOWS\System32\powrprof.dll
C:\WINDOWS\System32\kernel.appcore.dll
C:\WINDOWS\System32\profapi.dll
C:\WINDOWS\System32\gdi32full.dll
C:\WINDOWS\System32\msvcp_win.dll
C:\WINDOWS\System32\win32u.dll
C:\WINDOWS\System32\windows.storage.dll
C:\WINDOWS\System32\cfgmgr32.dll
C:\WINDOWS\System32\cryptsp.dll
C:\WINDOWS\System32\PSAPI.DLL
C:\WINDOWS\System32\combase.dll
C:\WINDOWS\System32\SHLWAPI.dll
C:\WINDOWS\System32\IMM32.DLL
C:\WINDOWS\System32\shcore.dll

Please file a bug about this at http://drmemory.org/issues

If I disable WebRoot security, then I get:

F:\DrMemory22\bin64>drmemory.exe c:\Perforce\client3\main\petro-sim\petro-sim.exe
~~Dr.M~~ WARNING: unable to locate results file: can't open F:\DrMemory22\drmemory\logs/resfile.8888 (code=2).
Dr. Memory failed to start the target application, perhaps due to
interference from invasive security software.
Try disabling other software or running in a virtual machine.