DReichLab / DReichLab/EIG

Smartrel does not yield any output

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C
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Description

Hello,

I am trying to use smartrel to find related individuals in my data. Unfortunately, I get no file of pairwise correlation coefficients. In my log file, I can see those who were above the set threshold, but there is no output file. Here are my scripts:

smartrel.perl

#!/usr/bin/perl

$ENV{'PATH'} = "../bin:$ENV{'PATH'}";

$command = "../bin/smartrel";
$command .= " -p par.smartrel > smartrel.log";
print("$command\n");
system("$command");

par.smartrel

genotypename:    data.geno
snpname:         data.snp
indivname:       data.ind
outputname:	 data_rel.coef
numeigs: 	 1
relthresh: 	 0.10
numoutlieriter:	 0
numthreads:	 32

I would add that I get no output file no matter the paramenters set in par.smartrel. Also, it looks like smartpca parameters can go inside smartrel's. Does this apply to all params or just some?

Could you please help me with this issue?

Best,
Andrei

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First steps

  1. Read the whole issue, then the project's contributing guide.
  2. Comment on the issue to say you are picking it up — it saves two people doing the same work.
  3. Fork the repository and make your change on a branch.
  4. Open a pull request that references the issue number.

Research direction

Start by reproducing the command from smartrel.perl with par.smartrel and inspect smartrel.log alongside the expected data_rel.coef output. Trace the smartrel entry point to determine why threshold matches produce no output file and verify which smartpca parameters are accepted; done means the documented configuration produces the expected coefficients file or clearly reports invalid parameters.

Written by the indexing model from the issue text.

Assessment

Tech stack
c, perl
Domain
bioinformatics
Issue type
Bug
Difficulty
4/5
Estimated time
3-5 days
Activity status
Stale
Clarity
Mostly clear
Newbie friendliness
28/100

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