DReichLab / DReichLab/AdmixTools
Feature request: More population differentiation analysis methods and statistics
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- Dominant language
- C
- Stars
- 235
- Forks
- 76
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Description
@bumblenick
Such as Fst, Gst, G'st, G''st, Rst, Фst etc.
Hello, this program is very good but it'd very helpful if it could support more differentiation analysis methods. I think especially useful would be ASD(Allele Sharing Distance), TVD(Total Variation Distance) and Est. since as far as I know no programs support these statistics currently in easy to use form.
Total Variation Difference is described here
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915815/
https://www.ncbi.nlm.nih.gov/pubmed/25788095
Asd
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869072/
Est
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0160413
Contributor guide
No contributing guide indexed for this repository
First steps
- Read the whole issue, then the project's contributing guide.
- Comment on the issue to say you are picking it up — it saves two people doing the same work.
- Fork the repository and make your change on a branch.
- Open a pull request that references the issue number.
Research direction
No files, tests, or entry points are mentioned. Start by reading the linked references for ASD, TVD, Est, and the listed differentiation statistics, then identify the project's current analysis scope. Done requires an agreed set of methods, definitions, inputs, outputs, and validation expectations.
Written by the indexing model from the issue text.
Assessment
- Tech stack
- c
- Domain
- bioinformatics
- Issue type
- Feature
- Difficulty
- 5/5
- Estimated time
- Over a week
- Activity status
- Stale
- Clarity
- Needs clarification
- Newbie friendliness
- 20/100