AllenInstitute / AllenInstitute/MIES
SweepFormula: P/x subtraction
Nobody has claimed this yet.
- Dominant language
- IGOR Pro
- Stars
- 30
- Forks
- 11
- Avg merge
- 1d 40m
- Merged PRs (30d)
- 8
Description
- Split into two issues: One for DAQ and one for display
- Think about doing it in the wavebuilder (check with experts and other software)
Implement p / x subtraction in MIES.
This is a technique used to subtract leak (aka linear) currents from current traces.
Desired workflow:
- User builds stimset in waveBuilder e.g. vClamp1
- At data acquisition, if user has activated p/x (user defines x; -4 is common), the stimulus set is modified by MIES and then acquired.
- In the first sweep, MIES acquires the waveBuilder vClamp1 sweep 1. In the same sweep, immediately following vClamp1,
vClamp1 / xis acquired.vClamp1 / xis repeated x times.
So, a stimset that looks like this:

Get acquired like this when x = -4:

-
When p/4 data is acquired, provide the user with the option of displaying the subtracted traces. The display of subtracted traces could be done using SF.
-
Subtraction formula: vClamp1 - (x * (average of
vclamp / xtraces)).
Contributor guide
First steps
- Read the whole issue, then the project's contributing guide.
- Comment on the issue to say you are picking it up — it saves two people doing the same work.
- Fork the repository and make your change on a branch.
- Open a pull request that references the issue number.
Research direction
The issue names waveBuilder, DAQ, display, and SF as the areas to investigate; begin by resolving the requested split between acquisition and display and checking how waveBuilder should participate. Confirm the workflow with project experts, then define completion around acquiring the paired p/x sweeps and offering the specified subtraction display.
Written by the indexing model from the issue text.
Assessment
- Domain
- data
- Issue type
- Feature
- Difficulty
- 5/5
- Estimated time
- Over a week
- Activity status
- Stale
- Clarity
- Mostly clear
- Newbie friendliness
- 30/100