Differential expression analysis for scRNA-seq

Need to develop some DE analysis that can apply to all the different scRNA-seq data types. Need to figure out a method of determining what DE analysis is best. Probably have a way of running all of them and comparing. Maybe make a nice Venn diagram of the identified DE genes from each method.

Questions for me to answer:
- What's a good quantification method for determining what DE methods work well.
- What DE methods are being kept up well and are widely applicable to different data types?
- Which seem to give the most biologically meaningful results? How to figure out what's biologically meaningful??