AlexsLemonade / AlexsLemonade/OpenScPCA-analysis

Create preliminary plots evaluating metaprograms from Neuroblastoma pilot

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#1,431 0 comments 0 reactions 1 assignee Claimed by @allyhawkins View on GitHub
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Description

### If you are filing this issue based on a specific GitHub Discussion, please link to the relevant Discussion.

_No response_

### Describe the goals of the changes to the analysis module.

We generated metaprograms on all Neuroblastoma samples in SCPCP000004 with `ews-nf`, which follows the same pipeline being implemented in `metafactory`. We want to create some initial figures that we can use to summarize these metaprograms.

### What will your pull request contain?

A script that reads in the metaprograms and outputs figures that might be helpful to show for this pilot group when presenting the `metafactory` workflow. The exact figures I want to make are TBD, but might include a heatmap of the top gene sets across each metaprogram, the correlation heatmap, and/or a UMAP of all neuroendocrine cells where cells are colored by metaprogram scores.

### Will you require additional software beyond what is already in the analysis module?

_No response_

### Will you require different computational resources beyond what the analysis module already uses?

_No response_

### If known, when do you expect to file the pull request?

_No response_

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