AlexsLemonade / AlexsLemonade/OpenScPCA-analysis
Explore use of pooled normal reference with inferCNV in solid tumors of interest
- Dominant language
- HTML
- Stars
- 16
- Forks
- 24
- Avg merge
- 3d 5h
- Merged PRs (30d)
- 4
Description
This Epic tracks work to explore if using pooled normal reference with inferCNV can improve classification of tumor vs normal cells across solid tumor projects of interest.
Noting this epic was originally opened to track work in Neuroblastoma samples from project `SCPCP000004`, but I've rethought this somewhat and have modified this epic description/name to generally track progress in the `infercnv-consensus-cell-type` module.
Contributor guide
Research direction
Start by reviewing the infercnv-consensus-cell-type module and the original Neuroblastoma context in project SCPCP000004. Compare whether pooled normal references improve tumor-versus-normal classification across the solid tumor projects of interest; done means the exploration has a documented conclusion and supporting results.
Written by the indexing model from the issue text.
Assessment
- Domain
- bioinformatics
- Issue type
- Feature
- Difficulty
- 5/5
- Estimated time
- Over a week
- Activity status
- Stale
- Clarity
- Needs clarification
- Newbie friendliness
- 20/100